✦ LIBER ✦
Fragile-X mutation proposed to block complete reactivation in females of an inactive X chromosome
✍ Scribed by Laird, Charles D.
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 180 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0148-7299
No coin nor oath required. For personal study only.
✦ Synopsis
I discuss two aspects of my proposal that fra(X) chromosomes exist in two states, imprinted and non-imprinted: why do males not imprint the fra(X); does the "Sherman paradox" rule out my proposal?
This proposal explains why:
(i) transmitting males are unaffected (they have inherited a fra(X) chromosome that was not