The probability of a heterozygote being affected was estimated from the distribution of frequencies of early-replicating fragile X [fra(X)I chromosome in normal and mentally retarded heterozygotes, taking into account the prior probabilities of 0.35 for mental retardation and 0.65 for normality. The
β¦ LIBER β¦
Fragile X frequency
β Scribed by Meisner, Lorraine F.
- Book ID
- 101442260
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 82 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0148-7299
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## Abstract Fragile X syndrome, the most common genetic disorder associated with mental retardation is caused by an expansion of the unstable CGG repeat within the __FMR1__ gene. Although overgrowth is not the main hallmark of this condition, the fragile X syndrome is usually included in the differ
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