𝔖 Bobbio Scriptorium
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Fragile X frequency

✍ Scribed by Meisner, Lorraine F.


Book ID
101442260
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
82 KB
Volume
37
Category
Article
ISSN
0148-7299

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The probability of a heterozygote being affected was estimated from the distribution of frequencies of early-replicating fragile X [fra(X)I chromosome in normal and mentally retarded heterozygotes, taking into account the prior probabilities of 0.35 for mental retardation and 0.65 for normality. The

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## Abstract Fragile X syndrome, the most common genetic disorder associated with mental retardation is caused by an expansion of the unstable CGG repeat within the __FMR1__ gene. Although overgrowth is not the main hallmark of this condition, the fragile X syndrome is usually included in the differ

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