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Fragile sites: Overview, occurrence in acute nonlymphocytic leukemia and effects of caffeine on expression

โœ Scribed by Thomas W. Glover; Jane Coyle-Morris; Rodman Morgan

Book ID
119103350
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
561 KB
Volume
19
Category
Article
ISSN
0165-4608

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To enhance the cytogenetic expression of the fragile X chromosome, we studied the effects of hyperoxia and caffeine on the induction of fragile Xq27.3. A lymphoblastoid cell line (GM 06912) derived from a fragile X male proband was cultured in RPMI 1640 containing 16% dialyzed fetal calf serum. The