𝔖 Bobbio Scriptorium
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Fragile histidine triad gene: potential cancer therapy?

✍ Scribed by Soni, Sushma

Book ID
120864125
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2001
Weight
139 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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✍ Guo, Zongyou; Johansson, Sonny L.; Rhim, Johng S.; Vishwanatha, Jamboor K. πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 610 KB

## BACKGROUND. The fragile histidine triad (FHIT) is frequently deleted and altered in many human cancers. Replacement of the FHIT gene into cancer cell lines lacking FHIT expression results in loss of tumorigenicity and tumor growth. METHODS. We investigated the status and function of the FHIT gen