Fragile chromosome 16(q22) cause a balanced translocation at the same point
✍ Scribed by J. M. García-Sagredo; C. San Román; M. E. Gallego Gómez; G. Lledo
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 867 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Carriers of the standard translocation t(11;22) (q23.3;q11.2) produce only one type of unbalanced offspring, a tertiary trisomy resulting into the karyotype 47,XX or XY, +der(22)t(11;22)(q23.3;q11.2), usually derived from the mother. The exception is one single patient 47,XY,t(11;22)(q23.3;q11.2), +
The cellular protooncogene MYC encodes a nuclear transcription factor that is involved in regulating important cellular functions, including cell cycle progression, differentiation, and apoptosis. Dysregulated MYC expression appears critical to the development of various types of malignancies, and t