## Abstract Mucopolysaccharidosis VII (MPS VII) is a lysosomal storage disorder characterized by a deficiency in Ξ²βglucuronidase activity, leading to systemic accumulation of poorly degraded glycosaminoglycans (GAG). Along with other morbidities, MPS VII is associated with pediatric spinal deformit
Fracture models in the lumbar sheep spine: A biomechanical investigation
β Scribed by Jan Heineck; Cornelius Haupt; Karin Werner; Stefan Rammelt; Hans Zwipp; Hans-Joachim Wilke
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 298 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0736-0266
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β¦ Synopsis
Abstract
The purpose of this study was to find out if a limited resection of the cranial vertebral body leaving the posterior wall intact is a sufficient model for AO type 3 fractures, or if additional resection of the posterior wall is necessary. In six, freshβfrozen, lumbar sheep spine specimens, the segmental stability was tested in three motion planes in a spine tester. First, the intact specimens were tested. Then, partial resection of the intervertebral disc L3/4 and resection of the cranial vertebral body of L4 was performed, leaving the posterior wall intact. This defect was tested without instrumentation and with a ventral monosegmental interlocking plate mounted. Then, the defect was extended to a total cranial resection, including the posterior wall, and the tests were subsequently repeated. The stability of both types of defects under the different conditions was compared. Without instrumentation, the total cranial resection showed significantly more ROM in flexion/extension and axial rotation than partial cranial resection. With the ventral interlocking plate mounted, the instability in total cranial resection was significantly higher in flexion/extension, with the relative relation even being increased. In axial rotation and lateral bending, the differences were equalized by the mounted plate. From a biomechanical point of view, total cranial resection including the posterior wall should be preferred as a sheep spine fracture model for AO type 3 fractures. Β© 2010 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 28:773β777, 2010
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