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Fractionation and antitumor activity of the water-in-soluble residue of Agaricus blazei fruiting bodies

✍ Scribed by Hirokazu Kawagishi; Ryuichi Inagaki; Teturo Kanao; Takashi Mizuno; Keishiro Shimura; Hitoshi Ito; Toshihiko Hagiwara; Takuji Nakamura

Publisher: Elsevier Science
Year: 1989
Tongue: English
Weight: 407 KB
Volume: 186
Category: Article
ISSN: 0008-6215
DOI: 10.1016/0008-6215(89)84040-6

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✦ Synopsis

Some polysaccharide-containing materials were successively extracted from the fruiting bodies of Agaricus bluzei with aqueous ammonium oxalate and sodium hydroxide, fractionated, and assayed for antitumor activity.

From chemical analyses and n.m.r. data, it was concluded that the most active fraction, FIII-2-b, was comprised of protein and a (l-6)-P-D-glucan.

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