Fractional anisotropy and mean diffusivity: comparison between 3.0-T and 1.5-T diffusion tensor imaging with parallel imaging using histogram and region of interest analysis
✍ Scribed by Yasutaka Fushimi; Yukio Miki; Tsutomu Okada; Akira Yamamoto; Nobuyuki Mori; Takashi Hanakawa; Shin-ichi Urayama; Toshihiko Aso; Hidenao Fukuyama; Ken-ichiro Kikuta; Kaori Togashi
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 191 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0952-3480
- DOI
- 10.1002/nbm.1139
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✦ Synopsis
Abstract
We performed a comparison study focusing on differences in fractional anisotropy (FA) and mean diffusivity (MD) between 3‐T and 1.5‐T diffusion tensor imaging (DTI) with parallel imaging. Thirty healthy volunteers underwent DTI with an eight‐channel phased‐array coil at both 3 T and 1.5 T. Histogram and region of interest (ROI) analyses were performed. Paired t tests were applied for statistical analysis. Signal‐to‐noise ratios of these regions were also measured. For histogram analysis, peak location of FA was significantly lower at 3 T than at 1.5 T (P = 0.04). Mean FA was significantly higher at 3 T than at 1.5 T (P = 0.002). Peak location of MD was significantly lower at 3 T than at 1.5 T (P < 0.001). Mean MD was significantly lower at 3 T than at 1.5 T (P < 0.001). In ROI analysis, FA was significantly larger at 3 T than at 1.5 T in the centrum semiovale (P < 0.001), middle cerebellar peduncle (P < 0.001), cerebral peduncle (P = 0.006), posterior limb of the internal capsule (P = 0.007), genu (P < 0.001) and splenium (P < 0.001). FA was significantly lower at 3 T than at 1.5 T in the globus pallidus (P < 0.001). MD was significantly smaller at 3 T than at 1.5 T in the globus pallidus (P = 0.007), thalamus (P < 0.001), centrum semiovale (P < 0.001), middle cerebellar peduncle (P < 0.001), cerebral peduncle (P = 0.01), posterior limb of the internal capsule (P < 0.001), genu (P = 0.01) and splenium (P < 0.001). Significant differences in FA and MD exist between 3 T and 1.5 T for whole‐brain histogram analysis and ROI analysis. Copyright © 2007 John Wiley & Sons, Ltd.