𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Fractal Geometry Study of DNA Binding Proteins

✍ Scribed by Jun Xu; Yang Chao; Runsheng Chen

Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
492 KB
Volume
171
Category
Article
ISSN
0022-5193

No coin nor oath required. For personal study only.

✦ Synopsis

The main aim of this paper is to search for three-dimensional structure homology between DNAbinding proteins. The run of a protein's main chain is depicted by a sequence, which is constituted by the fractal indices, where each index describes how twisted or extended a partial protein segment is. Two proteins are compared by constructing a dot matrix between two such sequences, and the matrix is searched for dot-concentrated rectangles which is an indication of tertiary homology. This new method is applied to DNA-binding proteins which are selected from Brookhaven Protein Data Bank, among which most contain a helix-turn-helix motif. The dot-matrix shows that there is tertiary homology between two motifs. Other interesting results are also presented in this paper.

📜 SIMILAR VOLUMES

Use of intrinsic protein fluorescence to
Use of intrinsic protein fluorescence to study DNA-protein binding
✍ R. Wickett; H.J. Li; I. Isenberg 📂 Article 📅 1972 🏛 Elsevier Science 🌐 English ⚖ 194 KB

When a polypeptide binds to DNA, the rotational mobility of a chromophore on the polypeptide is reduced. This simple fact makes it feasible to use polarization of fluorescence methods to study polypeptide-nucleic acid interaction. Previous (l-3) polarization of fluorescence studies of polypeptide-DN

Magnetic field activation of protein–DNA
Magnetic field activation of protein–DNA binding
✍ Hana Lin; Li Han; Martin Blank; Mark Head; Reba Goodman 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 148 KB 👁 2 views

The mechanisms involved in sensing, signaling, and coordinating changes resulting from magnetic field-induced stress show substantial similarities to those of heat shock, e.g., magnetic field-induced heat shock 70 gene (HSP70) expression involves heat shock factor (HSF) activation and heat shock ele

Immunologic studies of the low molecular
Immunologic studies of the low molecular weight DNA binding protein of murine oncornaviruses
✍ Cedric W. Long; Richard Berzinski; Raymond V. Gilden 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 French ⚖ 760 KB

## Abstract A low molecular weight, highly basic DNA‐binding protein was purified from several oncornaviruses by the sequential procedures of gel filtration in guanidine‐hydrochloride, DEAE‐cellulose chromatography and affinity chromatography on single‐stranded DNA sepharose. The binding protein fr