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FoxP3 genetic variants and risk of non-small cell lung cancer in the Chinese Han population

✍ Scribed by He, Yan-Qi; Bo, Qiao; Yong, Wei; Qiu, Zhi-Xin; Li, Ya-Lun; Li, Wei-Min

Book ID
122894896
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
242 KB
Volume
531
Category
Article
ISSN
0378-1119

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## Abstract Overexpression of MDM2 may attenuate the P53 stress response pathway through direct blocking of P53 transcriptional activity and mediating P53 degradation. Two promoter polymorphisms (one is a T to G substitution at the intronic P53‐response promoter, and the other is a 40‐bp insertion/