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Four tumor suppressor loci on chromosome 9q in bladder cancer: evidence for two novel candidate regions at 9q22.3 and 9q31

✍ Scribed by Simoneau, Maryse; Aboulkassim, Tahar O; LaRue, Hélène; Rousseau, François; Fradet, Yves


Book ID
110061738
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
443 KB
Volume
18
Category
Article
ISSN
0950-9232

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Candidate regions of tumor suppressor lo
✍ Naoto Kakinuma; Kazuyoshi Kohu; Masaaki Sato; Tatsuya Yamada; Motowo Nakajima; T 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 153 KB

Loss of heterozygosity (LOH) is an important event of tumorigenesis. In gastric cancer, we found a novel region of LOH in chromosome 9q having about 800 kb deletions at 9q31.1. The microsatellite marker D9S938 in that region exhibiting the highest LOH frequency, 56.5%. In addition, the LOH at 9q31.1