HLA class I allele promiscuity revisited
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Xiangyu Rao; Ilka Hoof; Ana Isabel C. A. Fontaine Costa; Debbie van Baarle; Can
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Article
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2011
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Springer-Verlag
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English
⚖ 641 KB
The peptide repertoire presented on human leukocyte antigen (HLA) class I molecules is largely determined by the structure of the peptide binding groove. It is expected that the molecules having similar grooves (i.e., belonging to the same supertype) might present similar/overlapping peptides. Howev