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Four epitopes on tumor necrosis factor-alpha defined by murine anti-tumor necrosis factor-alpha monoclonal antibodies

✍ Scribed by Bahija Karim; Roland Béliard; Jean-Jacques Huart; Dominique Bourel


Book ID
107908520
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
517 KB
Volume
41
Category
Article
ISSN
0165-2478

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## Abstract ## Objective The cyclic peptide WP9QY (YCWSQYLCY) was designed to mimic the most critical tumor necrosis factor α (TNFα) recognition loop on TNF receptor I, and it prevents interactions of TNFα with its receptor. We undertook this study to compare the effects of the WP9QY peptide on co