Foundations of Anesthesia: Basic Sciences for Clinical Practice, Second Edition

✍ Scribed by Hugh C. Hemmings BS MD PhD, Phillip M. Hopkins MB BS MD FRCA

• Publisher: Mosby
• Year: 2005
• Tongue: English
• Leaves: 917
• Edition: Second Edition
• Category: Library

✦ Synopsis

118 international experts provide you with complete coverage of basic and clinical science in anesthesiology. They emphasize the principles and clinical applications of molecular and cell biology, physiology, pharmacology, and physics and measurement. Over 700 full-color illustrations and easy-to-read tables and graphs help you understand every detail.Uses a visual approach with excellent full-color line illustrations.Includes a bonus CD-ROM that allows you to download all of the book's figures into PowerPoint® for electronic presentations. Refers only to key references from primary papers keeping information that is the most up-to-date.Contains new chapters on: Adverse Drug Reactions (Ch. 10), Sensory Systems (Ch. 22), Physiology of Pain (Ch. 23), Mechanisms of Anesthesia (Ch. 24), Consciousness & Cognition (Ch.29), Sleep & Anesthesia (Ch. 30), and Physiology & Pharmacology of Blood Coagulation (Ch. 53).Includes increased coverage of ultrasound in anesthesiology and clinical care.Offers new information on genomics and proteomics.Shows "clinical pearls" boxes in every chapter for added speed in reference. With 115 additional contributors

✦ Table of Contents

Cover......Page 1
ISBN 9780323037075......Page 2
Copyright......Page 3
Foreword......Page 8
Preface......Page 10
List of Contributors......Page 11
Dedication......Page 16
Molecular structure and biochemistry......Page 19
Biology of the cell......Page 31
Cell signaling......Page 47
Principles and techniques of molecular biology......Page 67
Genomics and proteomics......Page 87
Molecular physiology......Page 95
Sites of drug action......Page 107
Pharmacokinetic principles......Page 117
Anesthetic drug interactions......Page 135
Adverse drug reactions......Page 145
Basic physical principles......Page 153
Electromagnetism, light, and radiation......Page 159
Electrocardiography......Page 169
Electrophysiological monitoring......Page 179
Basic principles and limitations of hemodynamic monitoring......Page 189
Monitoring of gas concentrations......Page 205
Ultrasonography......Page 215
Statistics......Page 223
The structure and function of neurons......Page 237
The synapse......Page 249
Neurophysiology......Page 261
Sensory systems......Page 273
Physiology of pain......Page 283
General anesthetics: mechanisms of action......Page 303
Intravenous anesthetic agents......Page 311
Inhalational anesthetic agents......Page 327
Pharmacokinetics of inhalation anesthetics......Page 339
Anesthetic adjuvants and other CNS drugs......Page 353
Consciousness and cognition......Page 365
Sleep and anesthesia......Page 377
Opioids......Page 389
Nonopioid analgesic and anti-inflammatory drugs......Page 401
Pharmacology of local anesthetics......Page 409
Autonomic nervous system......Page 419
Voluntary motor systems –skeletal muscle, reflexes, and control of movement......Page 437
Neuromuscular junction physiology......Page 451
Neuromuscular junction pharmacology......Page 461
Vascular smooth muscle......Page 477
Cardiac physiology......Page 489
Cardiac electrophysiology......Page 501
Cardiovascular pharmacology......Page 515
Regulation and assessment of cardiac function......Page 527
The peripheral circulation......Page 541
Ischemic heart disease and heart failure......Page 553
Valvular heart disease......Page 567
Regulation of respiration......Page 579
Ventilation and perfusion......Page 589
Gas exchange......Page 599
Respiratory mechanics......Page 609
Lung function testing......Page 621
Drugs affecting the respiratory system......Page 631
Blood constituents and transfusion......Page 643
Hemostasis and coagulation......Page 651
The immune system......Page 663
Microbiology......Page 675
Ischemic brain injury......Page 687
Renal physiology......Page 703
Renal pathophysiology......Page 715
Regulation of blood volume and electrolytes......Page 724
Acid–base homeostasis......Page 739
Gut motility and secretions......Page 755
Nutrition, digestion, and absorption......Page 768
Physiology and pharmacology of nausea and vomiting......Page 779
Physiology and pharmacology of the liver......Page 789
Regulation of intermediary metabolism......Page 799
Endocrinology......Page 811
Thermoregulation......Page 825
Pregnancy......Page 839
Geriatrics......Page 851
Neonatology......Page 861
The pathophysiology of obesity and its implications for anesthesia......Page 871
Physiologic responses to surgery and trauma......Page 883
Sepsis......Page 891
Index......Page 899