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Foscan® (mTHPC) photosensitized macrophage activation: enhancement of phagocytosis, nitric oxide release and tumour necrosis factor-α-mediated cytolytic activity

✍ Scribed by Coutier, S; Bezdetnaya, L; Marchal, S; Melnikova, V; Belitchenko, I; Merlin, J L; Guillemin, F


Book ID
110002435
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
103 KB
Volume
81
Category
Article
ISSN
0007-0920

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## Abstract This study investigates the role of tumor nitric oxide (NO) and vascular regulation in tumor ulceration following high‐dose tumor necrosis factor‐α (TNF) treatment. Using TNF‐responsive (MethA) and nonresponsive (LL2) mouse tumors, tumor NO concentration was measured with an electrochem