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Forward Genetic Dissection of Immunity to Infection in the Mouse

✍ Scribed by Vidal, S.M.; Malo, D.; Marquis, J.-F.; Gros, P.


Book ID
120589310
Publisher
Annual Reviews
Year
2008
Tongue
English
Weight
495 KB
Volume
26
Category
Article
ISSN
0732-0582

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Resistance to infection is largely inherited rather than acquired, and is encoded by a definable set of host genes designated the 'resistome'. Logically speaking, piecemeal disruption of the resistome gives us the best chance to define it, and the most spectacular advances in understanding innate im