Forskolin suppresses the slow cyclic variations of glucose-induced electrical activity in pancreatic B cells
โ Scribed by J.C. Henquin; W. Schmeer; M. Nenquin; H.P. Meissner
- Book ID
- 117056487
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 333 KB
- Volume
- 120
- Category
- Article
- ISSN
- 0006-291X
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๐ SIMILAR VOLUMES
Low concentrations of tetraethylammonium chloride (TEA), which inhibit voltage-and Ca2+-sensitive K ยง channels (K ยง channels), were used to investigate whether these channels play a role in the control of glucoseinduced electrical activity (slow waves with spikes) in mouse pancreatic B-cells. Additi
The burst pattern of electrical activity recorded from pancreatic B-cells in response to 11 mM glucose shows a large islet to islet variability. The relationship between burst frequency and glucose sensing (the threshold for electrical activity and the graded increase in electrical response to gluco