Application of melt granulation technolo
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Madhav Vasanthavada; Yanfeng Wang; Thomas Haefele; Jay P. Lakshman; Manisha Mone
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Article
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2011
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John Wiley and Sons
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English
โ 414 KB
Development of modified-release oral tablets of drug products usually requires release-modifying polymers at the level of above 50% of the total weight. This makes the development of high-dose products, especially with doses in the range of 750-1000 mg, difficult because the tablet size becomes unac