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Formins initiate new actin filaments

✍ Scribed by Pollard, Thomas D.


Book ID
109911821
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
100 KB
Volume
4
Category
Article
ISSN
1465-7392

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## Abstract We review recent structural and biophysical studies of the mechanism of action of formins, proteins that direct the assembly of unbranched actin filaments for cytokinetic contractile rings and other cellular structures. Formins use free actin monomers to nucleate filaments and then rema