𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Formation of the B Ring in Steroids and Hopanoids from Squalene

✍ Scribed by B. Andes Hess Jr.

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
192 KB
Volume
2004
Category
Article
ISSN
1434-193X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A theoretical conformational study based on density functional calculations provides evidence that the sterol and nonsterol cyclizations of squalene to triterpenes are controlled by conformational effects as has been previously suggested. It was found that different conformers of a model system of squalene give rise to the chair−boat conformation found in the steroids and the chair−chair conformation of the pentacyclic 3‐deoxytriterpenes for their A and B rings. It is suggested that the enzymes play a key role in holding the substrate in the proper orientation for these cyclizations to occur. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)

📜 SIMILAR VOLUMES

Ring A Aromatic Steroids in the Pregnane
Ring A Aromatic Steroids in the Pregnane Series.
✍ Cavit Uyanik; Aslihan Malay; James R. Hanson; Peter B. Hitchcock; Serpil Tiryaki 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 18 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

ChemInform Abstract: Aplysiols A and B,
ChemInform Abstract: Aplysiols A and B, Squalene-Derived Polyethers from the Mantle of the Sea Hare Aplysia dactylomela.
✍ Emiliano Manzo; Margherita Gavagnin; Giuseppe Bifulco; Paola Cimino; Simone Di M 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 23 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v