𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Formation of the 11,12-diol as a metabolite of benzo(a)pyrene by rat skin in vivo

✍ Scribed by A. Weston; P.L. Grover; P. Sims


Book ID
115755670
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
393 KB
Volume
105
Category
Article
ISSN
0006-291X

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


The formation and persistence of benzo(a
✍ Stephen W. Ashurst; Gerald M. Cohen 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 645 KB

## Abstract The extent of reaction of benzo(__a__)pyrene with DNA and the formation of benzo(__a__)pyrene‐deoxyribonucleoside adducts in the skins of male Wistar rats were investigated. Following topical application of benzo(__a__)pyrene (200 nmoles), binding reached a maximum of 0,74 pmoles/mg DNA

In vivo formation of benzo (a) pyrene di
✍ Stephen W. Ashurst; Gerald M. Cohen 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 824 KB

## Abstract The hydrocarbon‐deoxyribonucleoside adducts formed in mouse skin DNA have been determined following topical application of an initiating dose of benzo(a)pyrene to Swiss mice, a strain shown to be susceptible to benzo(a)pyrene‐induced skin carcinogenesis. Several DNA‐bound products were