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Formation of Tetrahydro-β-carbolines and β-Carbolines during the Reaction of l -Tryptophan with d -Glucose

✍ Scribed by Rönner, Birgit; Lerche, Holger; Bergmüller, Wolfgang; Freilinger, Christine; Severin, Theodor; Pischetsrieder, Monika

Book ID
118745113
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
86 KB
Volume
48
Category
Article
ISSN
0021-8561

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Synthesis of Tetrahydro-β-carbolines and
Synthesis of Tetrahydro-β-carbolines and Studies of the Pictet–Spengler Reaction
✍ Pierre Ducrot; Cherif Rabhi; Claude Thal 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 270 KB

AbstractÐTetrahydro-b-carbolines have been prepared in a diastereomerically pure form by a short, ef®cient synthetic sequence consisting of reaction of a-aminoaldehydes with tryptamine. A study was made of the major factors affecting the stereoselectivity of the Pictet± Spengler reaction.