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Formation of physically stable amorphous phase of ibuprofen by solid state milling with kaolin

โœ Scribed by Subrata Mallick; Satyanarayan Pattnaik; Kalpana Swain; Pintu K. De; Arindam Saha; Gaurisankar Ghoshal; Arijit Mondal


Book ID
116437791
Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
492 KB
Volume
68
Category
Article
ISSN
0939-6411

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Formation of physically stable amorphous
โœ Manish K. Gupta; Adam Vanwert; Robin H. Bogner ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 259 KB

Each of four drugs (ketoprofen, indomethacin, naproxen, and progesterone) was milled with Neusilin (amorphous magnesium aluminosilicate) to effect conversion from crystalline to amorphous states, and the physical stability of the resultant drugs was investigated. Ball milling the drugs alone for 48