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Formation of Nε-Dnp Lysine during deprotection of Nε-Fmoc lysine in Nim-DNP-histidine-containing peptides

✍ Scribed by Jean-Claude Gesquiére; Jamila Najib; Thierry Letailleur; Pierrette Maes; André Tartar


Book ID
104224993
Publisher
Elsevier Science
Year
1993
Tongue
French
Weight
272 KB
Volume
34
Category
Article
ISSN
0040-4039

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Synthesis of Nα-Boc-Nε-tetrabenzyl-DTPA-
✍ Dr John S. Davies; Loai Al-Jamri 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 127 KB

## Abstract Two building blocks, Boc‐Lys(Bn~4~‐DTPA)‐OH and Fmoc‐Lys($\hbox{Bu}^{\rm t}\_{4}$‐DTPA)‐OH have been synthesized via the acylation of the ε‐amino group of __N__^α^‐protected lysine, using suitably protected tetra‐esters of diethylene triamine pentaacetic acid (DTPA), a ligand with wide