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Formation of N δ -Cyanoornithine from N G -Hydroxy- l -arginine and Hydrogen Peroxide by Neuronal Nitric Oxide Synthase: Implications for Mechanism †

✍ Scribed by Clague, Melissa J.; Wishnok, John S.; Marletta, Michael A.


Book ID
125966686
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
164 KB
Volume
36
Category
Article
ISSN
0006-2960

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✍ Bernd Clement; Elke Schnörwangen; Thomas Kämpchen; Peter Mordvintcev; Alexander 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 509 KB

## Abstract __N__^ω^‐Hydroxy‐L‐arginine (2) was prepared by a multi‐stage synthesis; the key step was the addition of hydroxylamine to the protected cyanamide 8. The presence of __N__‐hydroxyguanidines was confirmed, above all, by ^15^N‐NMR investigations. ^15^__N__^ω^‐Hydroxy‐L‐arginine (2) was co