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Formation of N-(glutathion-S-methylene)-4-aminoazobenzene following metabolic oxidation of the N-methyl group of the carcinogen, N-methyl-4-aminoazobenzene

โœ Scribed by B. Ketterer; S.K.S. Srai; B. Waynforth; D.L. Tullis; F.E. Evans; F.F. Kadlubar


Book ID
113136475
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
914 KB
Volume
38
Category
Article
ISSN
0009-2797

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Synthesis of the hepatocarcinogen N-meth
โœ Jen-Kun Lin; James A. Miller ๐Ÿ“‚ Article ๐Ÿ“… 1969 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 215 KB

The new compound N-methyl-4-nitrosoacetanilide w a ~. coupled with ~niIine-~H(ring-G) in ethanol-acetic acid and the resulting azoamide was hydrolyzed in alkali to give a high yield o j N-methyl-4-aminoazobenzene labelled in the prime ring. ## INTRODUCTION. N-Methyl-4-aminoazobenzene, a hepatocar