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Formation of N-glucuronide of desmethylimipramine in the dog

โœ Scribed by M. H. Bickel; R. Minder; C. di Francesco


Book ID
112654730
Publisher
Springer
Year
1973
Tongue
English
Weight
362 KB
Volume
29
Category
Article
ISSN
1420-682X

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The pharmacokinetic disposition of lorazepam was investigated in sham-operated aneshetized dogs, dogs with hepatic devascularization, and dogs with total splanchnic devascularization following i.v. administration of 0.3 mg per kg of the drug. In sham-operated dogs, lorazepam distribution was extensi