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Formation of multilayer aggregates of hepatocytes cultured on ligand-coated surfaces

โœ Scribed by Jun Feng Liang; Toshihiro Akaike

Book ID
110226816
Publisher
Springer Netherlands
Year
1999
Tongue
English
Weight
82 KB
Volume
21
Category
Article
ISSN
0141-5492

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โœ Takayoshi Tokiwa; Junko Kano; Xian-Yian Meng; Raman Bahulekar; Makoto Kodama ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 474 KB

Adult rat hepatocytes in primary culture formed floating, non-spheroidal aggregates on the surfaces coated with 1 % polyacrylamide. In the cells of aggregates, DNA synthetic capacity was limited, but albumin secreting capacity was maintained at least for 2 weeks. These properties were influenced by