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Formation of Modified Cytosine Residues in the Presence of Depurinated DNA.

✍ Scribed by Claus Rentel; Xiaojing Wang; Michael Batt; Christine Kurata; Jay Oliver; Hans Gaus; Achim H. Krotz; James V. McArdle; Daniel C. Capaldi

Book ID
101982798
Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

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## Abstract Metabolic conversion of endogenous estrogens, estradiol (E~2~) and estrone (E~1~), to the catechol estrogens 4‐hydroxyE~1~(E~2~) [4‐OHE~1~(E~2~)] has been implicated in the initiation of cancer in rodents and humans. Evidence collected in our laboratories has shown that 4‐OHE~1~(E~2~) a