𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Formation of Hydrogen-Bonding Adduct between 1-Phyenyl-2-Amino Pyrimidine and Vaniline, C17H13N3O2

✍ Scribed by Dr. I. S. Ahmed Farag; Dr. A. M. Gad; Dr. A. M. El-Shabiny; Dr. V. B. Rybakov

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
372 KB
Volume
28
Category
Article
ISSN
0232-1300

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The adduct compound was prepared by condensation of equimolar quantities of analar vaniline and 1‐phenyl‐2‐amino pyrimidine in absolute ethyl alcohol. Prismatic crystals were obtained with the crystallographic data: a = 12.901 (6), b = 19.297 (9), c = 6.828 (3) Å, γ = 102.67 (2)°, V = 1657.9 Å^3^, Z = 4, F.W. = 291.31, D~x~ = 1.17 g/cm^3^, space group P2/n, R = 0.038 and R~w~ = 0.036.

The intensity data were collected on an Enraf Nonius CAD‐4 computer controlled diffractometer using MoKα radiation. The structure was solved by direct method and refined by full matrix least‐squares using anisotropic temperature factor of all atoms, except for hydrogen ones, which were treated isotropically. A full discussion was given to explain: a) the occurrence of the condensation process between the OH‐group of vaniline and the heterocyclic N‐atom in position 5 of the pyrimidine cycle and b) why this condensation does not take place between the amino‐group of the pyrimidine compound and the aldehydic group of vaniline to give a Schiff base.

📜 SIMILAR VOLUMES

NMR of Enaminones Part 3—1H, 13C and 17O
NMR of Enaminones Part 3—1H, 13C and 17O NMR Spectroscopic Studies of Acyclic and Cyclic N-Aryl Enaminones: Substituent Effects and Intramolecular Hydrogen Bonding
✍ Jin-Cong Zhuo 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 303 KB 👁 2 views

17O, 13C and 1H NMR spectra for paraand meta-substituted 4-arylaminopent-3-en-2-ones (acyclic enaminones, 1 and 2) and 3-arylaminocyclohex-2-en-1-ones (cyclic enaminones, 3 and 4) are reported. The 17O, 13C and 1H shift values of these enaminones correlate well with and constants in the correlations

Stereoselective Michael addition of 6-am
Stereoselective Michael addition of 6-amino-1,3-dimethyl-2,4-pyrimidinedione to the exocyclic methylene of three sesquiterpene lactones. 1H and 13C NMR evidence of a new C-C bond and lactam formation
✍ Eduardo Dfaz; Hector Barrios; Jose Luis Nava; Raul G. Enriquez; Angel Guzmán; Le 📂 Article 📅 1997 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 330 KB

## Abstract The Stereoselective addition of the pyrimidine derivative 1 to the exocyclic methylene of the α,β unsaturated dehydrocostus lactone 2, Ivalin acetate 3 and Zaluzanin A diacetate 4, was achieved resulting in a new C‐C bond formation. In the cases of compounds 3 and 4, after the addition,