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Formation of DNA adducts and tumor growth delay following intratumoral administration of DTI-015

โœ Scribed by William J. Bodell; Donald D. Giannini; Saira Singh; Dennis Pietronigro; Victor A. Levin


Book ID
110435780
Publisher
Springer US
Year
2003
Tongue
English
Weight
83 KB
Volume
62
Category
Article
ISSN
0167-594X

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## Exposure of experimental animals to toxaphene induces hepatic cytochrome P-450 (CYP). Although chronic administration of toxaphene to mice was found to cause an increased incidence of liver tumors, a mechanism for its carcinogenicity has yet to be elucidated. We investigated two potential mecha