Formation of carboxamides with N,N,N′,N′-tetramethyl (succinimido) uronium tetrafluoroborate in aqueous / organic solvent systems

✍ Scribed by Willi Bannwarth; Reinhard Knorr

• Publisher: Elsevier Science
• Year: 1991
• Tongue: French
• Weight: 236 KB
• Volume: 32
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)92032-x

✦ Synopsis

N,N,N',N'-tetramethyl (succinimido) uronium tetrafluoroborate can be employed for an effective and fast formation of carboxamides even in mixed aqueous/organic solvent systems. In this respect it represents an alternative to carbodiimide reagents applied for the same purpose.

One of the standard procedures for the preparation of carboxamides proceeds via activated