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Formation of a resistive region at the anode end in DNA capillary electrophoresis

โœ Scribed by Olga Bilenko; Dmitri Gavrilov; Boris Gorbovitski; Vera Gorfinkel; Michael Gouzman; Georgy Gudkov; Vyacheslav Khozikov; Olga Khozikov; Olga Kosobokova; Nadia Lifshitz; Serge Luryi; Andrew Stepoukhovitch; Marina Tcherevishinick; Georgy Tyshko


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
241 KB
Volume
24
Category
Article
ISSN
0173-0835

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Succinimide formation at Asn 55 in the c
โœ Boxu Yan; Sean Steen; David Hambly; John Valliere-Douglass; Tim Vanden Bos; Scot ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 354 KB

We investigated the formation and stability of succinimide, an intermediate of deamidation events, in recombinant monoclonal antibodies (mAbs). During the course of an analytical development study of an IgG1 mAbs, we observed that a specific antibody population could be separated from the main produ