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Formation of a prostaglandin A2-glutathione conjugate in L1210 mouse leukemia cells

โœ Scribed by Judy Parker; Helmut Ankel

Book ID
115783024
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
968 KB
Volume
43
Category
Article
ISSN
0006-2952

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The 4-quinolone antibiotics nalidixic acid and ciprofloxacin are potent inhibitors of the bacterial type II topoisomerase DNA gyrase. Treatment of mouse L1210 leukemia cells with these drugs resulted in a delayed inhibition of cell proliferation. Prior to inhibition of cell proliferation, there was