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Formation of a nine-subunit complex by HLA class II glycoproteins and the invariant chain

โœ Scribed by Roche, Paul A.; Marks, Michael S.; Cresswell, Peter J.


Book ID
109779066
Publisher
Nature Publishing Group
Year
1991
Tongue
English
Weight
595 KB
Volume
354
Category
Article
ISSN
0028-0836

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The influence of the class II-associated invariant chain (Ii) on the presentation of the protein antigens hen egg-white lysozyme (HEL) and ribonuclease A (RNase) was investigated. For this purpose the Ii- rat-2 fibroblasts were transfected with I-Ak genes with or without Ii. Transfectants expressing