Formation and structure of PEI/DNA complexes: quantitative analysis
β Scribed by Hou, Sen; Ziebacz, Natalia; Wieczorek, Stefan A.; Kalwarczyk, Ewelina; Sashuk, Volodymyr; Kalwarczyk, Tomasz; Kaminski, Tomasz S.; Holyst, Robert
- Book ID
- 120390752
- Publisher
- Royal Society of Chemistry
- Year
- 2011
- Tongue
- English
- Weight
- 267 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1744-683X
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The main goal of this study was to determine the effects of polyethylenimine (PEI) molecular weight and structure (750 kDa, 25 kDa, 2 kDa branched, and 25 kDa linear PEI) and the nitrogen/phosphate (N/P) molar ratio on the physical properties and transfection efficiencies of PEI/DNA complexes. Fouri
Previous transfection studies of cationic peptoid polymers (N-substituted polyglycines) and cationic lipitoid polymers (peptoid-phospholipid conjugates) have shown that only the polymers which possessed a repeating (cationic, hydrophobic, hydrophobic) substituent sequence are efficient in gene trans