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Formation and Export of the Glutathione Conjugate of 4-Hydroxy-2,3-E-nonenal (4-HNE) in Hepatoma Cells

✍ Scribed by Ronald B. Tjalkens; Lanz W. Cook; Dennis R. Petersen


Book ID
115567374
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
88 KB
Volume
361
Category
Article
ISSN
0003-9861

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To study the possible involvement of reactive oxygen species (ROS) in the tumor biology of human renal-cell carcinoma (RCC), we analyzed 35 cases of RCC for 2 parameters of oxidative damage: 8-hydroxy-2'-deoxyguanosine (8-OHdG), a mutation-prone DNA-base-modified product, was measured by means of hi