Forensic application of organ-specific antigens
β Scribed by Keiichi Takahama
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 390 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0379-0738
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β¦ Synopsis
A highly sensitive sandwich enzyme immunoassay for organ-specific antigen is described for use in forensic practice. The sandwich enzyme immunoassays for specific antigens to the liver (LSA), the small intestine (sucrase-isomaltase), and the heart (cardiac troponin I) were developed. High levels of antigen could be detected to exist in forensic materials, and it is clearly possible to differentiate between samples from these stabbed organs and those originating from other stabbed organs. In addition, a sandwich enzyme immunoassay for prostate-specific antigen ( y-seminoprotein, y-sm) was developed for sex discrimination of blood and bloodstains. The ratio of y-sm to hemoglobin was significantly higher in male adults than in female adults.
π SIMILAR VOLUMES
Blood samples from 507 unrelated persons in Northrhine-Westphalia and from 254 paternity cases were tested for the Lutheran blood group antigens Lu a and Lu b. The gene frequencies were found to be 0.03 (=Lu ~) and 0.969 (=Lub).