𝔖 Bobbio Scriptorium
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Forensic application of organ-specific antigens

✍ Scribed by Keiichi Takahama


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
390 KB
Volume
80
Category
Article
ISSN
0379-0738

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✦ Synopsis


A highly sensitive sandwich enzyme immunoassay for organ-specific antigen is described for use in forensic practice. The sandwich enzyme immunoassays for specific antigens to the liver (LSA), the small intestine (sucrase-isomaltase), and the heart (cardiac troponin I) were developed. High levels of antigen could be detected to exist in forensic materials, and it is clearly possible to differentiate between samples from these stabbed organs and those originating from other stabbed organs. In addition, a sandwich enzyme immunoassay for prostate-specific antigen ( y-seminoprotein, y-sm) was developed for sex discrimination of blood and bloodstains. The ratio of y-sm to hemoglobin was significantly higher in male adults than in female adults.


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