Foreign body reaction to biomaterials
β Scribed by James M. Anderson; Analiz Rodriguez; David T. Chang
- Book ID
- 116885524
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 645 KB
- Volume
- 20
- Category
- Article
- ISSN
- 1044-5323
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## Abstract Although biomaterials have been used in the clinical setting for a long time, little is known of the molecular mechanisms underlying the foreignβbody reaction (FBR). A good understanding of these mechanisms is requisite for the controlled regulation of the FBR needed to prevent adverse
## Abstract Matrix metalloproteinases (MMPs) can degrade structural components within the extracellular matrix and at the cellular surface producing changes in cellular behavior (i.e., adhesion and migration) and subsequent pathological responses (i.e., the foreign body reaction and wound healing).