Structural features for the mechanism of
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Antonello Merlino; Giovanna Avella; Sonia Di Gaetano; Angela Arciello; Renata Pi
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Article
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2008
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Cold Spring Harbor Laboratory Press
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English
⚖ 210 KB
## Abstract A specialized class of RNases shows a high cytotoxicity toward tumor cell lines, which is critically dependent on their ability to reach the cytosol and to evade the action of the ribonuclease inhibitor (RI). The cytotoxicity and antitumor activity of bovine seminal ribonuclease (BSRNas