Food deprivation and stimulant self-administration in rats: differences between cocaine andd-amphetamine

✍ Scribed by S. D. Glick; P. A. Hinds; J. N. Carlson

• Publisher: Springer
• Year: 1987
• Tongue: English
• Weight: 332 KB
• Volume: 91
• Category: Article
• ISSN: 0033-3158
• DOI: 10.1007/bf00518194

✦ Synopsis

The effects of food deprivation (24 h) on response rates of rats self-administering d-amphetamine and cocaine were compared. Food deprivation clearly increased rates of responding for both drugs but did so to a significantly greater extent for cocaine than for d-amphetamine. Consistent with other findings, the results suggest that the neural substrates underlying cocaine and d-amphetamine reinforcement are not identical.