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Fontolizumab shows efficacy in moderate-to-severe Crohn's

Book ID
120849936
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2006
Weight
121 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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Fontolizumab in moderate to severe Crohn
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## Background: The safety and efficacy of fontolizumab, a humanized anti-interferon gamma antibody, was investigated in patients with Crohn's disease (CD). Elevated gut mucosal levels of interferon gamma, a key cytokine involved in the inflammatory process of CD, are associated with disease symptom