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Following the rule: formation of the 6-helix bundle of the fusion core from severe acute respiratory syndrome coronavirus spike protein and identification of potent peptide inhibitors

✍ Scribed by Jieqing Zhu; Gengfu Xiao; Yanhui Xu; Fang Yuan; Congyi Zheng; Yueyong Liu; Huimin Yan; David K Cole; John I Bell; Zihe Rao; Po Tien; George F Gao

Book ID
116288441
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
259 KB
Volume
319
Category
Article
ISSN
0006-291X

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## Abstract Severe acute respiratory coronavirus (SARS‐CoV) spike (S) glycoprotein fusion core consists of a six‐helix bundle with the three C‐terminal heptad repeat (HR2) helices packed against a central coiled‐coil of the other three N‐terminal heptad repeat (HR1) helices. Each of the three perip