✦ LIBER ✦

Follow-up of a familial translocation t(10;16) with an unusual segregation pattern

✍ Scribed by Resta, Robert G.; Luthardt, Frederick; Kapur, Raj

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 23 KB
Volume: 63
Category: Article
ISSN: 0148-7299
DOI: 10.1002/(sici)1096-8628(19960517)63:2<363::aid-ajmg7>3.0.co;2-u

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✦ Synopsis

reported on a four-generation family with an unusual segregation pattern involving a translocation t(lO;l6)(q26.3;pl3.1). All relatives either had a balanced or unbalanced translocation. We report on five additional relatives, none of whom have a normal karyotype. This unusual segregation pattern may be due to chance or be the result of meiotic drive.