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Folic acid inhibits serum-induced activation of egf-receptor (EGFR) promoter in colon cancer cells

✍ Scribed by Nagothu, Kiran K.; Rishi, Arun K.; Jaszewski, Richard; Majumdar, Adhip P.N.


Book ID
122057938
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
170 KB
Volume
124
Category
Article
ISSN
0016-5085

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## Abstract Deoxycholic acid (DCA) has been implicated in colorectal carcinogenesis in humans with effects on proliferation and apoptosis, mediated at least in part by activation of transcription factors nuclear factor kappa B (NF‐κB), activator protein 1 (AP‐1) and protein kinase C (PKC) enzymes.