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Folic Acid and Vitamin B12 Supplementation Improves Arterial Function and Structure in Subjects with Subnormal Intake

✍ Scribed by K.S. Woo; P. Chook; T.W.C. Yip; S.K. Kwong; Y.J. Hu; X.S. Huang; G.G. Wang; M.J. Wu; Y.M. Liu; C.W.K. Lam; D.S. Celermajer

Book ID: 119255826
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 87 KB
Volume: 17
Category: Article
ISSN: 1443-9506
DOI: 10.1016/j.hlc.2008.05.480

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Using homocysteine as a functional marker, we determined optimal folic acid, vitamin B 12 , and vitamin B 6 dosages in 21 pediatric sickle cell disease (SCD) patients (11 HbSS, 10 HbSC;(7)(8)(9)(10)(11)(12)(13)(14)(15)(16). Daily supplements of folic acid (400, 700, or 1,000 lg), vitamin B 12 (1, 3,