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Folic acid and chromosome breakage III. Types and frequencies of spontaneous chromosome aberrations in proliferating lymphocytes

✍ Scribed by Xin-Zhi Li; John A. Reidy; Virginia A. Wheeler; Andrew T.L. Chen


Book ID
113254854
Publisher
Elsevier Science
Year
1986
Weight
274 KB
Volume
173
Category
Article
ISSN
0165-7992

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The incidence of structural chromosome aberrations and the rate of sister chromatid exchanges (SCE) was investigated in lymphocyte cultures from a patient with typical Fanconi's anemia and his parents. The rate of SCEs was found to be normal. In experiments with the alkylating agent Trenimon the SCE