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Folding Simulations of a De Novo Designed Protein with a βαβ Fold

✍ Scribed by Qi, Yifei; Huang, Yongqi; Liang, Huanhuan; Liu, Zhirong; Lai, Luhua

Book ID
119206008
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
552 KB
Volume
98
Category
Article
ISSN
0006-3495

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## Abstract Stereochemistry could be a powerful variable for conformational tune up of polypeptides for de novo design. It may be also useful probe of possible role of interamide energetics in selection and stabilization of conformation. The homopolypeptides Ac–Xxx~30~–NHMe, with Xxx = Ala, Val, an