Folding Amphipathic Helices Into Membranes: Amphiphilicity Trumps Hydrophobicity
✍ Scribed by Mónica Fernández-Vidal; Sajith Jayasinghe; Alexey S. Ladokhin; Stephen H. White
- Book ID
- 116663515
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 996 KB
- Volume
- 370
- Category
- Article
- ISSN
- 0022-2836
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Hydrophobins are small secreted fungal proteins rich in hydrophobic amino acids with a characteristic hydropathy pattern and conserved location of eight cysteine residues. It was previously shown that purified SC3p hydrophobin of Schizophyllum commune self-assembles at hydrophilic/hydrophobic interf
Liposomes consisting of egg yolk phosphatidylcholine and hydrophobic peptides Nps-and C1--+H,-(Met-Met-Leu),-OEt ( n = 6-10) with various polypeptide chain lengths were prepared by the sonication method. The conformation of the peptides incorporated into the liposomes was examined by CD spectroscopy