The molecular basis for the well-established hierarchy of susceptibility to valproic acidinduced neural tube defects in inbred mouse strains was examined using in situ transcription and anti-sense RNA amplification methodologies with both univariate and multivariate analyses of the resulting gene ex
Folate antagonism following teratogenic exposure to diphenylhydantoin
β Scribed by Netzloff, Michael L. ;Streiff, Richard R. ;Frias, Jaime L. ;Rennert, Owen M.
- Book ID
- 112216888
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 341 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0040-3709
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
An in vivo-in vitro test system with high sensitivity to teratogens has been developed and validated. A single acute intra-peritoneal injection of teratogens (1 8) and non-teratogens (13) was administered to pregnant rats on the 12th day after fertilisation, and uteri were removed after 16 h by lapa
## Abstract On days 12β16 of gestation pregnant rats were exposed to heavy distillate (HD), the highestβboiling material derived from the solvent refined coalβII (SRCβII) process, and the litters were examined at day 21. Adverse biological effects were observed in the group of animals exposed to an